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Immunology Innate Immunity Macrophage / Inflamm.

Recombinant human CX3CL1 protein (ab9820)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant human CX3CL1 protein
    See all CX3CL1 proteins and peptides
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      42 kDa
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9820 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Additional notes

        The biological activity of this product is determined by its ability to chemoattract human T-lymphocytes using a concentration range of 5.0-10.0 ng/ml.
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • A 152E5.2
        • AB030188
        • ABCD 3
        • ABCD3
        • AI848747
        • C-X3-C motif chemokine 1
        • C3Xkine
        • Chemokine (C-X3-C motif) ligand 1
        • Chemokine C X3 C motif ligand 1
        • Chemokine CX3C Motif Ligand 1
        • CX3C membrane anchored chemokine
        • CX3C membrane-anchored chemokine
        • Cx3cl1
        • CXC 3
        • CXC3
        • CXC3C
        • D8Bwg0439e
        • FKN
        • Fractalkine
        • Neurotactin
        • NTN
        • NTT
        • Processed fractalkine
        • SCYD 1
        • SCYD1
        • Small inducible cytokine D1
        • Small inducible cytokine subfamily D (Cys X3 Cys) member 1
        • small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
        • Small inducible cytokine subfamily D member 1
        • Small-inducible cytokine D1
        • X3CL1_HUMAN
        see all
      • Function

        The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
      • Tissue specificity

        Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
      • Sequence similarities

        Belongs to the intercrine delta family.
      • Post-translational
        modifications

        A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.
        O-glycosylated with core 1 or possibly core 8 glycans.
      • Cellular localization

        Secreted and Cell membrane.
      • Target information above from: UniProt accession P78423 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab9820? Please let us know so that we can cite the reference in this datasheet.

    ab9820 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • A 152E5.2
      • AB030188
      • ABCD 3
      • ABCD3
      • AI848747
      • C-X3-C motif chemokine 1
      • C3Xkine
      • Chemokine (C-X3-C motif) ligand 1
      • Chemokine C X3 C motif ligand 1
      • Chemokine CX3C Motif Ligand 1
      • CX3C membrane anchored chemokine
      • CX3C membrane-anchored chemokine
      • Cx3cl1
      • CXC 3
      • CXC3
      • CXC3C
      • D8Bwg0439e
      • FKN
      • Fractalkine
      • Neurotactin
      • NTN
      • NTT
      • Processed fractalkine
      • SCYD 1
      • SCYD1
      • Small inducible cytokine D1
      • Small inducible cytokine subfamily D (Cys X3 Cys) member 1
      • small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
      • Small inducible cytokine subfamily D member 1
      • Small-inducible cytokine D1
      • X3CL1_HUMAN
      see all
    • Function

      The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
    • Tissue specificity

      Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
    • Sequence similarities

      Belongs to the intercrine delta family.
    • Post-translational
      modifications

      A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.
      O-glycosylated with core 1 or possibly core 8 glycans.
    • Cellular localization

      Secreted and Cell membrane.
    • Target information above from: UniProt accession P78423 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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