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Recombinant Human Complement factor B protein (His tag) (ab276729)

Recombinant Human Complement factor B protein (His tag) (ab276729)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human Complement factor B protein (His tag)
    See all Complement factor B proteins and peptides
  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    P00751
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSNLSPQLC LMPFILGLLS GGVTTTPWSL ARPQGSCSLE GVEIKGGSFR LLQEGQALEY VCPSGFYPY PVQTRTCRST GSWSTLKTQD QKTVRKAECR AIHCPRPHDF ENGEYWPRSP YYNVSDEIS FHCYDGYTLR GSANRTCQVN GRWSGQTAIC DNGAGYCSNP GIPIGTRKVG SQYRLEDSV TYHCSRGLTL RGSQRRTCQE GGSWSGTEPS CQDSFMYDTP QEVAEAFLSS LTETIEGVD AEDGHGPGEQ QKRKIVLDPS GSMNIYLVLD GSDSIGASNF TGAKKCLVNL IEKVASYGV KPRYGLVTYA TYPKIWVKVS EADSSNADWV TKQLNEINYE DHKLKSGTNT KKALQAVYS MMSWPDDVPP EGWNRTRHVI ILMTDGLHNM GGDPITVIDE IRDLLYIGKD RKNPREDYL DVYVFGVGPL VNQVNINALA SKKDNEQHVF KVKDMENLED VFYQMIDESQ SLSLCGMVW EHRKGTDYHK QPWQAKISVI RPSKGHESCM GAVVSEYFVL TAAHCFTVDD KEHSIKVSV GGEKRDLEIE VVLFHPNYNI NGKKEAGIPE FYDYDVALIK LKNKLKYGQT IRPICLPCT EGTTRALRLP PTTTCQQQKE ELLPAQDIKA LFVSEEEKKL TRKEVYIKNG DKKGSCERDA QYAPGYDKV KDISEVVTPR FLCTGGVSPY ADPNTCRGDS GGPLIVHKRS RFIQVGVISW GVVDVCKNQ KRQKQVPAHA RDFHINLFQV LPWLKEKLQD EDLGFL
    • Predicted molecular weight

      85 kDa including tags
    • Molecular weight information

      The recombinant human CFB consists of 750 amino acids and predicts a molecular mass of 84.5 kDa.
    • Amino acids

      1 to 764
    • Tags

      His tag C-Terminus
    • Additional sequence information

      Predicted N-terminus: Thr 26.
  • Specifications

    Our Abpromise guarantee covers the use of ab276729 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.4
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • C3/C5 convertase
      • Complement factor B
      • Glycine-rich beta glycoprotein
      • PBF2
      • Properdin factor B
      see all
    • Relevance

      Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
    • Cellular localization

      Plasma membrane and Secreted

Images

  • SDS-PAGE - Recombinant Human Complement factor B protein (ab276729)
    SDS-PAGE - Recombinant Human Complement factor B protein (ab276729)
    SDS-PAGE analysis of ab276729

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276729? Please let us know so that we can cite the reference in this datasheet.

    ab276729 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • C3/C5 convertase
    • Complement factor B
    • Glycine-rich beta glycoprotein

    Images

    • SDS-PAGE - Recombinant Human Complement factor B protein (ab276729)
      SDS-PAGE - Recombinant Human Complement factor B protein (ab276729)
      SDS-PAGE analysis of ab276729

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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