Recombinant Human Complement factor B protein (His tag) (ab276729)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 90% SDS-PAGE
- Endotoxin level:
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
-
Product name
Recombinant Human Complement factor B protein (His tag)
See all Complement factor B proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MGSNLSPQLC LMPFILGLLS GGVTTTPWSL ARPQGSCSLE GVEIKGGSFR LLQEGQALEY VCPSGFYPY PVQTRTCRST GSWSTLKTQD QKTVRKAECR AIHCPRPHDF ENGEYWPRSP YYNVSDEIS FHCYDGYTLR GSANRTCQVN GRWSGQTAIC DNGAGYCSNP GIPIGTRKVG SQYRLEDSV TYHCSRGLTL RGSQRRTCQE GGSWSGTEPS CQDSFMYDTP QEVAEAFLSS LTETIEGVD AEDGHGPGEQ QKRKIVLDPS GSMNIYLVLD GSDSIGASNF TGAKKCLVNL IEKVASYGV KPRYGLVTYA TYPKIWVKVS EADSSNADWV TKQLNEINYE DHKLKSGTNT KKALQAVYS MMSWPDDVPP EGWNRTRHVI ILMTDGLHNM GGDPITVIDE IRDLLYIGKD RKNPREDYL DVYVFGVGPL VNQVNINALA SKKDNEQHVF KVKDMENLED VFYQMIDESQ SLSLCGMVW EHRKGTDYHK QPWQAKISVI RPSKGHESCM GAVVSEYFVL TAAHCFTVDD KEHSIKVSV GGEKRDLEIE VVLFHPNYNI NGKKEAGIPE FYDYDVALIK LKNKLKYGQT IRPICLPCT EGTTRALRLP PTTTCQQQKE ELLPAQDIKA LFVSEEEKKL TRKEVYIKNG DKKGSCERDA QYAPGYDKV KDISEVVTPR FLCTGGVSPY ADPNTCRGDS GGPLIVHKRS RFIQVGVISW GVVDVCKNQ KRQKQVPAHA RDFHINLFQV LPWLKEKLQD EDLGFL -
Predicted molecular weight
85 kDa including tags -
Molecular weight information
The recombinant human CFB consists of 750 amino acids and predicts a molecular mass of 84.5 kDa. -
Amino acids
1 to 764 -
Tags
His tag C-Terminus -
Additional sequence information
Predicted N-terminus: Thr 26.
Specifications
Our Abpromise guarantee covers the use of ab276729 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
SDS-PAGE
-
Form
Lyophilized -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.4
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
-
Alternative names
- C3/C5 convertase
- Complement factor B
- Glycine-rich beta glycoprotein
see all -
Relevance
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. -
Cellular localization
Plasma membrane and Secreted
Images
-
SDS-PAGE - Recombinant Human Complement factor B protein (ab276729)SDS-PAGE analysis of ab276729
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276729 has not yet been referenced specifically in any publications.
Preparation and Storage
- C3/C5 convertase
- Complement factor B
- Glycine-rich beta glycoprotein
Images
-
SDS-PAGE - Recombinant Human Complement factor B protein (ab276729)SDS-PAGE analysis of ab276729