Recombinant Human CEACAM5 protein (Fc Chimera) (ab276358)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human CEACAM5 protein (Fc Chimera) -
Purity
> 95 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Human -
Predicted molecular weight
98 kDa including tags -
Molecular weight information
The recombinant human CEACAM5 consists of 889 amino acids and predicts a molecular mass of 98.1 kDa. -
Amino acids
1 to 685 -
Tags
Fc tag C-Terminus -
Additional sequence information
Fc region of human IgG1.Predicted N-terminus: Lys 35.
Specifications
Our Abpromise guarantee covers the use of ab276358 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- Carcinoembryonic antigen
- Carcinoembryonic antigen related cell adhesion molecule 5
- CD66e
see all -
Relevance
The CEA gene family belongs to the immunoglobulin gene superfamily (IgSF) and comprises a large number of genes. The cell surface associated CEA proteins are heavily glycosylated, abundantly expressed and multifunctional. The human carcinoembryonic antigen (CEA) family can be divided into two subgroups according to the means of anchorage of member glycoproteins to the cell membrane: glycophosphatidyl inositol (GPI) linkage and transmembrane linkage. GPI-linked CEA family members include CEA (CD66e), non-specific cross-reacting antigen (NCA, CD66c), CEA gene-family members 6 (CGM6, CD66b) and 2 (CGM2). Transmembrane-linked members include biliary glycoprotein (BGP, Human C-CAM-L and C-CAM-S, CD66a), CGM1(CD66d) and CGM7. Recent evidence suggests the GPI-linked members tend to be up-regulated in human tumors, whereas the transmembrane-linked members tend to be down-regulated. -
Cellular localization
Cell membrane. Attached to the membrane by a GPI-anchor.
Images
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SDS-PAGE - Recombinant Human CEACAM5 protein (Fc Chimera) (ab276358)SDS-PAGE analysis of ab276358
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276358 has not yet been referenced specifically in any publications.
Preparation and Storage
- Carcinoembryonic antigen
- Carcinoembryonic antigen related cell adhesion molecule 5
- CD66e
Images
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SDS-PAGE - Recombinant Human CEACAM5 protein (Fc Chimera) (ab276358)SDS-PAGE analysis of ab276358