Recombinant Human CDNF protein (Fc Chimera) (ab276682)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human CDNF protein (Fc Chimera)
See all CDNF proteins and peptides -
Purity
> 95 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MWCASPVAVV AFCAGLLVSH PVLTQGQEAG GRPGADCEVC KEFLNRFYKS LIDRGVNFSL DTIEKELISF CLDTKGKENR LCYYLGATKD AATKILSEVT RPMSVHMPAM KICEKLKKLD SQICELKYEK TLDLASVDLR KMRVAELKQI LHSWGEECRA CAEKTDYVNL IQELAPKYAA THPKTEL -
Predicted molecular weight
45 kDa including tags -
Molecular weight information
The recombinant human CDNF consists 401 amino acids and predicts a molecular mass of 45.2 kDa. -
Amino acids
1 to 187 -
Tags
Fc tag C-Terminus -
Additional sequence information
Fc region of human IgG1.Predicted N-terminus: Gln 25.
Specifications
Our Abpromise guarantee covers the use of ab276682 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.4
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- Arginine rich mutated in early stage tumors like 1
- ARMET L1
- ARMET like protein 1
see all -
Function
Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. -
Tissue specificity
Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. -
Sequence similarities
Belongs to the ARMET family. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276682 has not yet been referenced specifically in any publications.
Preparation and Storage
- Arginine rich mutated in early stage tumors like 1
- ARMET L1
- ARMET like protein 1