Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human CDNF protein (Fc Chimera) (ab276682)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: Fc tag C-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human CDNF protein (Fc Chimera)
    See all CDNF proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q49AH0-1

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MWCASPVAVV AFCAGLLVSH PVLTQGQEAG GRPGADCEVC KEFLNRFYKS LIDRGVNFSL DTIEKELISF CLDTKGKENR LCYYLGATKD AATKILSEVT RPMSVHMPAM KICEKLKKLD SQICELKYEK TLDLASVDLR KMRVAELKQI LHSWGEECRA CAEKTDYVNL IQELAPKYAA THPKTEL

    • Predicted molecular weight

      45 kDa including tags

    • Molecular weight information

      The recombinant human CDNF consists 401 amino acids and predicts a molecular mass of 45.2 kDa.

    • Amino acids

      1 to 187

    • Tags

      Fc tag C-Terminus

    • Additional sequence information

      Fc region of human IgG1.Predicted N-terminus: Gln 25.

    • Specifications

    Our Abpromise guarantee covers the use of ab276682 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.4
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • Arginine rich mutated in early stage tumors like 1
      • ARMET L1
      • ARMET like protein 1
      • ARMET-like protein 1
      • ARMETL 1
      • ARMETL1
      • CDNF
      • CDNF_HUMAN
      • Cerebral dopamine neurotrophic factor
      • Conserved dopamine neurotrophic factor
      see all

    • Function

      Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.

    • Tissue specificity

      Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.

    • Sequence similarities

      Belongs to the ARMET family.

    • Cellular localization

      Secreted.
    • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human CDNF protein (ab276682)
    SDS-PAGE - Recombinant Human CDNF protein (ab276682)
    SDS-PAGE analysis of ab276682

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab276682? Please let us know so that we can cite the reference in this datasheet.

ab276682 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Arginine rich mutated in early stage tumors like 1
  • ARMET L1
  • ARMET like protein 1

Images

  • SDS-PAGE - Recombinant Human CDNF protein (ab276682)
    SDS-PAGE - Recombinant Human CDNF protein (ab276682)
    SDS-PAGE analysis of ab276682

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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