Recombinant human CD80 protein (Active) (ab271371)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Active: Yes
- Tags: His tag C-Terminus, DDDDK tag C-Terminus, Avi tag C-Terminus
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant human CD80 protein (Active)
See all CD80 proteins and peptides -
Biological activity
Active in a CTLA4:CD80 TR-FRET assay.
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Purity
>= 90 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
VIHVTKEVKE VATLSCGHNV SVEELAQTRI YWQKEKKMVL TMMSGDMNIW PEYKNRTIFD ITNNLSIVIL ALRPSDEGTY ECVVLKYEKD AFKREHLAEV TLSVKADFPT PSISDFEIPT SNIRRIICST SGGFPEPHLS WLENGEELNA INTTVSQDPE TELYAVSSKL DFNMTTNHSF MCLIKYGHLR VNQTFNWNTT KQEHFPDN -
Predicted molecular weight
28 kDa including tags -
Molecular weight information
Protein runs at higher MW on SDS-PAGE due to glycosylation. -
Amino acids
35 to 242 -
Tags
His tag C-Terminus , DDDDK tag C-Terminus , Avi tag C-Terminus -
Additional sequence information
Genbank: NM_005191
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Preparation and Storage
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Alternative names
- Activation B7-1 antigen
- B lymphocyte activation antigen B7
- B7
see all -
Function
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. -
Tissue specificity
Expressed on activated B-cells, macrophages and dendritic cells. -
Sequence similarities
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
Images
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Functional Studies - Recombinant Human CD80 protein (Tagged) (ab271371)
Functional analysis of ab271371.
Note: B7-1 = CD80.
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SDS-PAGE - (ab271371)SDS-PAGE analysis of ab271371.