Recombinant Human CD38 protein (His tag) (PE) (ab269981)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 90% SDS-PAGE
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human CD38 protein (His tag) (PE)
See all CD38 proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
VPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGA FISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDM FTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTV SRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWV IHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPE DSSCTSEI -
Predicted molecular weight
31 kDa including tags -
Amino acids
43 to 300 -
Tags
His tag C-Terminus -
Additional sequence information
Labeled with PE. NM_001775
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Conjugation
PE. Ex: 488nm, Em: 575nm
Preparation and Storage
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Alternative names
- Acute lymphoblastic leukemia cells antigen CD38
- ADP ribosyl cyclase
- ADP ribosyl cyclase 1
see all -
Function
Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. -
Tissue specificity
Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. -
Sequence similarities
Belongs to the ADP-ribosyl cyclase family. -
Developmental stage
Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human CD38 protein (Phycoerythrin) (ab269981)
SDS-PAGE analysis of ab269981 on a 4-20% gel with Coomassies staining.
Lane1: ab269981 (8 μg).
Lane 2: MW marker.
Lane 3: Unlabeled CD38 (4 μg).
Lane 4: RPE (4 μg).
Lane 5: MW marker.
