Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human CD34 protein (ab126924)

Key features and details

  • Expression system: CHO cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human CD34 protein
    See all CD34 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Greater than 95% by SDS-PAGE gel and HPLC analyses.

  • Endotoxin level

  • Expression system

    CHO cells

  • Accession

    P28906

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      LDNNGTATPE LPTQGTFSNV STNVSYQETT TPSTLGSTSL HPVSQHGNEA TTNITETTVK FTSTSVITSV YGNTNSSVQS QTSVISTVFT TPANVSTPET TLKPSLSPGN VSDLSTTSTS LATSPTKPYT SSSPILSDIK AEIKCSGIRE VKLTQGICLE QNKTSSCAEF KKDRGEGLAR VLCGEEQADA DAGAQVCSLL LAQSEVRPQC LLLVLANRTE ISSKLQLMKK HQSDLKKLGI LDFTEQDVAS HQSYSQKT

    • Predicted molecular weight

      27 kDa

    • Amino acids

      33 to 290

    • Specifications

    Our Abpromise guarantee covers the use of ab126924 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C.

      Constituent: 0.16% Sodium phosphate

    • Reconstitution
      Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20oC to -80oC.

    General Info

    • Alternative names

      • CD34
      • CD34 antigen
      • CD34 molecule
      • CD34_HUMAN
      • Cluster designation 34
      • cluster of differentiation 34
      • Hematopoietic progenitor cell antigen CD34
      • HPCA1
      • Mucosialin
      • OTTHUMP00000034733
      • OTTHUMP00000034734
      see all

    • Function

      Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

    • Tissue specificity

      Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.

    • Sequence similarities

      Belongs to the CD34 family.

    • Developmental stage

      On early hematopoietic progenitor cells.

    • Post-translational
      modifications

      Highly glycosylated.
      Phosphorylated on serine residues by PKC.

    • Cellular localization

      Membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab126924? Please let us know so that we can cite the reference in this datasheet.

ab126924 has not yet been referenced specifically in any publications.

Preparation and Storage

  • CD34
  • CD34 antigen
  • CD34 molecule

Images

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