Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human CD300a protein (Fc Chimera His Tag) (ab185418)

Key features and details

  • Expression system: Mammalian
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituent: 100% PBS

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilised protein in 3X PBS. Please aliquot the reconstituted solution and store at

    General Info

    • Alternative names

      • CD300 antigen-like family member A
      • CD300a
      • CD300a antigen
      • CD300a molecule
      • CLM-8
      • CLM8_HUMAN
      • CMRF 35 H9
      • CMRF-35-H9
      • CMRF35-H
      • CMRF35-H9
      • CMRF35-like molecule 8
      • CMRF35H
      • CMRF35H leukocyte immunoglobulin like receptor
      • CMRF35H9
      • IgSF12
      • Immunoglobulin superfamily member 12
      • Inhibitory receptor protein 60
      • IRC1
      • IRC1/IRC2
      • IRC2
      • IRp60
      • Leukocyte membrane antigen
      • Mast cell derived paired immunoglobulin like receptor 1
      • NK inhibitory receptor
      • Polymeric immunoglobulin receptor 4
      see all

    • Function

      Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.

    • Tissue specificity

      Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.

    • Sequence similarities

      Belongs to the CD300 family.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Post-translational
      modifications

      Phosphorylated on tyrosine.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

References (0)

Publishing research using ab185418? Please let us know so that we can cite the reference in this datasheet.

ab185418 has not yet been referenced specifically in any publications.

Images

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