Recombinant Human CD200R protein (Tagged) (ab185859)
Key features and details
- Expression system: Mammalian
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: Fc tag C-Terminus
- Suitable for: HPLC, SDS-PAGE
Preparation and Storage
-
Alternative names
- CD 200R
- CD200 cell surface glycoprotein receptor
- CD200 receptor 1
see all -
Function
Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. -
Tissue specificity
Expressed in granulocytes, monocytes, most T cells, neutrophils, basophils and a subset of NK, NKT and B cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells. -
Sequence similarities
Belongs to the CD200R family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Post-translational
modificationsThe mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
