Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Mammalian
Purity: > 95% SDS-PAGE
Endotoxin level:
Tags: Fc tag C-Terminus
Suitable for: HPLC, SDS-PAGE

Alternative names
- CD 200R
- CD200 cell surface glycoprotein receptor
- CD200 receptor 1
- Cd200r1
- Cell surface glycoprotein CD200 receptor 1
- Cell surface glycoprotein OX2 receptor
- Cell surface glycoprotein OX2 receptor 1
- cell surface glycoprotein receptor CD200
- CRTR 2
- CRTR2
- HCRTR2
- MO2R1_HUMAN
- MOX2 receptor
- MOX2R
- OX2R
see all
Function

Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Tissue specificity

Expressed in granulocytes, monocytes, most T cells, neutrophils, basophils and a subset of NK, NKT and B cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.
Sequence similarities

Belongs to the CD200R family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Post-translational
modifications

The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform.
Cellular localization

Secreted and Cell membrane.
Target information above from: UniProt accession Q8TD46 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

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