Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human CCL23 protein (Active) (ab9931)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human CCL23 protein (Active)
    See all CCL23 proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      13 kDa

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9931 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized

      • Additional notes

        The biological activity of this product is determined by its ability to chemoattract human T-cells using a concentration range of 10.0-50.0 ng/ml.

        Previously labelled as Macrophage Inflammatory Protein 3. 

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • C C motif chemokine ligand 23
        • C-C motif chemokine 23
        • C6 beta chemokine
        • CCL 23
        • CCL23
        • CCL23(30-99)
        • CCL23_HUMAN
        • Chemokine (C C motif) ligand 23
        • Chemokine CC motif ligand 23
        • ck beta 8
        • CK-beta-8
        • CKB 8
        • CKB-8
        • Ckb-8-1
        • CKB8
        • Hmrp-2a
        • Macrophage inflammatory protein 3
        • MIP 3
        • MIP-3
        • MIP3
        • MPIF 1
        • MPIF-1
        • MPIF1
        • Myeloid progenitor inhibitory factor 1
        • OTTHUMP00000163948
        • SCYA 23
        • SCYA23
        • Small inducible cytokine A 23
        • Small inducible cytokine subfamily A (Cys-Cys), member 23
        • Small inducible cytokine subfamily A, member 23
        • Small-inducible cytokine A23
        see all

      • Function

        Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.

      • Tissue specificity

        High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients.

      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab9931? Please let us know so that we can cite the reference in this datasheet.

    ab9931 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C C motif chemokine ligand 23
      • C-C motif chemokine 23
      • C6 beta chemokine
      • CCL 23
      • CCL23
      • CCL23(30-99)
      • CCL23_HUMAN
      • Chemokine (C C motif) ligand 23
      • Chemokine CC motif ligand 23
      • ck beta 8
      • CK-beta-8
      • CKB 8
      • CKB-8
      • Ckb-8-1
      • CKB8
      • Hmrp-2a
      • Macrophage inflammatory protein 3
      • MIP 3
      • MIP-3
      • MIP3
      • MPIF 1
      • MPIF-1
      • MPIF1
      • Myeloid progenitor inhibitory factor 1
      • OTTHUMP00000163948
      • SCYA 23
      • SCYA23
      • Small inducible cytokine A 23
      • Small inducible cytokine subfamily A (Cys-Cys), member 23
      • Small inducible cytokine subfamily A, member 23
      • Small-inducible cytokine A23
      see all

    • Function

      Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.

    • Tissue specificity

      High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients.

    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

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