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Immunology Innate Immunity Complement Classical Pathway

Recombinant Human C1r protein (ab152248)

Recombinant Human C1r protein (ab152248)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Wheat germ
  • Purity: > 80% SDS-PAGE
  • Tags: GST tag N-Terminus
  • Suitable for: WB, SDS-PAGE, ELISA

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Description

  • Product name

    Recombinant Human C1r protein
  • Purity

    > 80 % SDS-PAGE.
    Purity of ab152248 is >80% by CBR (commassie blue reagent = SDS-PAGE). Please contact techinical support regarding the purity of a specific batch.
  • Expression system

    Wheat germ
  • Accession

    P00736
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITV PTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPP GKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRS KLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELYTE ASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHC PYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKL RYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQV LHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKA RIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPV CGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTA AHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDE SYNFEGDIALLELENSVTLGPNLLPICLPDSDTFYDLGLMGYVSGFGVME EKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDAC QGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKE MEEED
    • Predicted molecular weight

      103 kDa including tags
    • Amino acids

      1 to 705
    • Tags

      GST tag N-Terminus

Preparation and Storage

  • Alternative names

    • C1 R
    • C1R
    • C1R_HUMAN
    • Complement C1r
    • Complement C1r subcomponent
    • Complement C1r subcomponent light chain
    • Complement C1r subcomponent precursor
    • Complement component 1 r subcomponent
    • Complement component 1 subcomponent r
    see all
  • Function

    C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
  • Sequence similarities

    Belongs to the peptidase S1 family.
    Contains 2 CUB domains.
    Contains 1 EGF-like domain.
    Contains 1 peptidase S1 domain.
    Contains 2 Sushi (CCP/SCR) domains.
  • Post-translational
    modifications

    The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
  • Target information above from: UniProt accession P00736 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant Human C1r protein (ab152248)
    SDS-PAGE - Recombinant Human C1r protein (ab152248)
    12.5% SDS-PAGE stained with Coomassie Blue.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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