Recombinant human BMP5 protein (Active) (ab245809)
Key features and details
- Expression system: CHO cells
- Purity: >= 95% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, HPLC, SDS-PAGE
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Product name
Recombinant human BMP5 protein (Active)
See all BMP5 proteins and peptides -
Biological activity
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
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Purity
>= 95 % SDS-PAGE.
=95 % by HPLC. -
Expression system
CHO cells -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
AANKRKNQNRNKSSSHQDSSRMSSVGDYNTSEQKQACKKHELYVSFRDLG WQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPK PCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGCH -
Predicted molecular weight
16 kDa -
Amino acids
317 to 454 -
Additional sequence information
Full length mature chain without signal peptide, without propeptide. ab245809 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.
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Preparation and Storage
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Alternative names
- BMP 5
- BMP-5
- Bmp5
see all -
Function
Induces cartilage and bone formation. -
Tissue specificity
Expressed in the lung and liver. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
