Recombinant Human beta 5 Defensin protein (ab190997)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Suitable for: SDS-PAGE, HPLC
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Product name
Recombinant Human beta 5 Defensin protein
See all beta 5 Defensin proteins and peptides -
Purity
> 95 % SDS-PAGE.
The purity of ab190997 is greater than 98% by SDS-PAGE gel and HPLC analyses. -
Endotoxin level
Expression system
Escherichia coliAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
GLDFSQPFPS GEFAVCESCK LGRGKCRKEC LENEKPDGNC RLNFLCCRQR I -
Predicted molecular weight
6 kDa -
Amino acids
28 to 78 -
Additional sequence information
This product is the mature full length protein from aa 28 to 78. The signal peptide is not included.
Specifications
Our Abpromise guarantee covers the use of ab190997 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
HPLC
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Form
Lyophilized -
Additional notes
Avoid inhalation. Avoid contact with eyes, skin and clothing.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C.
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ReconstitutionFor lot specific reconstitution information please contact our Scientific Support Team.
General Info
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Alternative names
- BD5
- Beta defensin 105 precursor
- DEFB105
see all -
Relevance
Defensins (a and ß) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the ß-defensins by the pairing of their three disulfide bonds. To date, six human ß-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. ß-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The ß-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. ß-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. -
Cellular localization
Secreted
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab190997 has not yet been referenced specifically in any publications.
Preparation and Storage
- BD5
- Beta defensin 105 precursor
- DEFB105