Antibodies, Proteins, Kits and Reagents for Life Science

Recombinant Human BD-3 protein (ab255991)

Key features and details

Expression system: Escherichia coli
Purity: >= 95% SDS-PAGE
Endotoxin level:
Suitable for: SDS-PAGE

Alternative names
- BD 3
- BD-3
- BD3
- beta 103
- Beta defensin 103A
- Beta defensin 103A precursor
- Beta defensin 3
- Beta-defensin 103
- Beta-defensin 3
- D103A_HUMAN
- DEF B3
- DEFB 103
- DEFB 103A
- DEFB 3
- DEFB-3
- DEFB103
- DEFB103A
- DEFB103B
- DEFB3
- Defensin
- Defensin beta 103A
- Defensin beta 3
- Defensin like protein
- Defensin-like protein
- HBD 3
- hBD-3
- HBD3
- HBP 3
- HBP3
- mBD3
see all
Function

Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
Tissue specificity

Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
Sequence similarities

Belongs to the beta-defensin family.
Cellular localization

Secreted.
Target information above from: UniProt accession P81534 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human BD-3 protein (ab255991)

SDS-PAGE analysis of ab255991 (1 μg) under non-reducing (Lane 1) and reducing (Lane 2) conditions.

4-20% Tris-Glycine gel. Coomassie Blue staining.

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