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Signal Transduction Growth Factors/Hormones TNF

Recombinant Human BCMA protein (ab268360)

Recombinant Human BCMA protein (ab268360)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human BCMA protein
    See all BCMA proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q02223
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Molecular weight information

      Approx 6 kDa by SDS-PAGE
    • Amino acids

      1 to 54
  • Specifications

    Our Abpromise guarantee covers the use of ab268360 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      Constituent: PBS

      Lyophilized from 0.2 um filtered solution

    • Reconstitution
      A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Upon reconstitution the protein can be stored in working aliquits at 4C for 1 month or -20C for 6 months with a carrier protein with out detectabile losss of activity.

    General Info

    • Alternative names

      • B cell maturation antigen
      • B cell maturation factor
      • B cell maturation protein
      • B-cell maturation protein
      • BCM
      • BCMA
      • CD269
      • CD269 antigen
      • TNFRSF17
      • TNR17_HUMAN
      • Tumor necrosis factor receptor superfamily member 17
      see all
    • Function

      Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
    • Tissue specificity

      Expressed in mature B-cells, but not in T-cells or monocytes.
    • Involvement in disease

      Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
    • Sequence similarities

      Contains 1 TNFR-Cys repeat.
    • Cellular localization

      Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
    • Target information above from: UniProt accession Q02223 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • SDS-PAGE - Recombinant human BCMA protein (ab268360)
    SDS-PAGE - Recombinant human BCMA protein (ab268360)

    SDS-PAGE analysis of ab268456.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab268360? Please let us know so that we can cite the reference in this datasheet.

    ab268360 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • B cell maturation antigen
    • B cell maturation factor
    • B cell maturation protein

    Images

    • SDS-PAGE - Recombinant human BCMA protein (ab268360)
      SDS-PAGE - Recombinant human BCMA protein (ab268360)

      SDS-PAGE analysis of ab268456.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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