Recombinant Human Axl protein (Tagged) (ab271369)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 90% SDS-PAGE
- Tags: DDDDK tag N-Terminus
- Suitable for: SDS-PAGE
-
Product name
Recombinant Human Axl protein (Tagged)
See all Axl proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Expression system
Baculovirus infected Sf9 cells -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
HRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEEL KEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIA ICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPF MKHGDLHSFLLYSRLGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRD LAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLA DRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPA DCLDGLYALMSRCWELNPQDRPSFTELREDLENTLKALPPAQEPDEILYV NMDEGGGYPEPPGAAGGADPPTQPDPKDSCSCLTAAEVHPAGRYVLCPST TPSPAQPADRGSPAAPGQEDGA -
Predicted molecular weight
49 kDa including tags -
Amino acids
473 to 894 -
Tags
DDDDK tag N-Terminus -
Additional sequence information
Cytoplasmic domain.
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Preparation and Storage
-
Alternative names
- Adhesion related kinase
- AI323647
- Ark
see all -
Function
May function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor. -
Tissue specificity
Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt