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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Recombinant Human Axl protein (Tagged) (ab271369)

Recombinant Human Axl protein (Tagged) (ab271369)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Baculovirus infected Sf9 cells
  • Purity: > 90% SDS-PAGE
  • Tags: DDDDK tag N-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human Axl protein (Tagged)
    See all Axl proteins and peptides
  • Purity

    > 90 % SDS-PAGE.

  • Expression system

    Baculovirus infected Sf9 cells
  • Accession

    P30530
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      HRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEEL KEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIA ICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPF MKHGDLHSFLLYSRLGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRD LAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLA DRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPA DCLDGLYALMSRCWELNPQDRPSFTELREDLENTLKALPPAQEPDEILYV NMDEGGGYPEPPGAAGGADPPTQPDPKDSCSCLTAAEVHPAGRYVLCPST TPSPAQPADRGSPAAPGQEDGA
    • Predicted molecular weight

      49 kDa including tags
    • Amino acids

      473 to 894
    • Tags

      DDDDK tag N-Terminus
    • Additional sequence information

      Cytoplasmic domain.

Preparation and Storage

  • Alternative names

    • Adhesion related kinase
    • AI323647
    • Ark
    • Axl
    • AXL oncogene
    • AXL receptor tyrosine kinase
    • AXL transforming gene
    • AXL transforming sequence/gene
    • EC 2.7.10.1
    • JTK11
    • Oncogene AXL
    • Tyro7
    • Tyrosine protein kinase receptor UFO
    • Tyrosine-protein kinase receptor UFO
    • UFO
    • UFO_HUMAN
    see all
  • Function

    May function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor.
  • Tissue specificity

    Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localization

    Membrane.
  • Target information above from: UniProt accession P30530 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • Functional Studies - Recombinant Human Axl protein (Tagged) (ab271369)
    Functional Studies - Recombinant Human Axl protein (Tagged) (ab271369)

    SDS-PAGE analysis of ab271369.

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