Recombinant HIV1 integrase protein (ab49082)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: His tag C-Terminus, His tag N-Terminus
- Suitable for: ELISA, WB
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Product name
Recombinant HIV1 integrase protein
See all HIV1 integrase proteins and peptides -
Biological activity
Strongly reacts with human HIV positive serum -
Purity
> 95 % SDS-PAGE. -
Expression system
Escherichia coli -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Amino acids
9 to 289 -
Tags
His tag C-Terminus , His tag N-Terminus
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Preparation and Storage
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Alternative names
- HIV
- Human Immunodeficiency virus 1
- IN
- Integrase
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Relevance
Integrase is an enzyme, a product of the HIV1 Gag/Pol gene; the other two enzymes being reverse transcriptase and protease. The human immunodeficiency virus (HIV-1) uses an enzyme, a so-called integrase, to carry out the integration of its viral DNA into the host chromosome thereby tricking the host cell machinery into making viral proteins. The HIV-1 integrase is a protein of 32 kDa and is composed of three domains. No cellular homologue of HIV integrase has been described, so potential inhibitors to this enzyme could be relatively nontoxic.
