Recombinant Hepatitis B Surface Antigen AD protein (ab193473)
Key features and details
- Expression system: Saccharomyces cerevisiae
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE, ELISA, WB
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Product name
Recombinant Hepatitis B Surface Antigen AD protein -
Purity
> 95 % SDS-PAGE. -
Expression system
Saccharomyces cerevisiae -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Predicted molecular weight
24 kDa -
Additional sequence information
Surface antigen Ad.
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Preparation and Storage
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Alternative names
- HBsAg
- Hep B surface antigen
- Hepatitis B Virus major surface antigen
see all -
Relevance
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. -
Cellular localization
Cell Membrane