Recombinant S. pyogenes Streptolysin O (Hemolytic streptococcus) protein (ab126650)
Key features and details
- Expression system: Escherichia coli
- Suitable for: SDS-PAGE
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Product name
Recombinant S. pyogenes Streptolysin O (Hemolytic streptococcus) protein
See all Streptolysin O (Hemolytic streptococcus) proteins and peptides -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Streptococcus pyogenes -
Sequence
MSNKKTFKKY SRVAGLLTAA LIIGNLVTAN AESNKQNTAS TETTTTNEQP KPESSELTTE KAGQKTDDML NSNDMIKLAP KEMPLESAEK EEKKSEDKKK SEEDHTEEIN DKIYSLNYNE LEVLAKNGET IENFVPKEGV KKADKFIVIE RKKKNINTTP VDISIIDSVT DRTYPAALQL ANKGFTENKP DAVVTKRNPQ KIHIDLPGMG DKATVEVNDP TYANVSTAID NLVNQWHDNY SGGNTLPART QYTESMVYSK SQIEAALNVN SKILDGTLGI DFKSISKGEK KVMIAAYKQI FYTVSANLPN NPADVFDKSV TFKELQRKGV SNEAPPLFVS NVAYGRTVFV KLETSSKSND VEAAFSAALK GTDVKTNGKY SDILENSSFT AVVLGGDAAE HNKVVTKDFD VIRNVIKDNA TFSRKNPAYP ISYTSVFLKN NKIAGVNNRT EYVETTSTEY TSGKINLSHR GAYVAQYEIL WDEINYDDKG KEVITKRRWD NNWYSKTSPF STVIPLGANS RNIRIMAREC TGLAWEWWRK VIDERDVKLS KEINVNISGS TLSPYGSITY K -
Predicted molecular weight
64 kDa -
Amino acids
1 to 571
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Preparation and Storage
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Alternative names
- Streptolysin O
- Streptolysin O (Thiol-activated cytolysin) slo
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Relevance
Streptolysin O (SLO) is a membrane-damaging extracellular toxin produced by hemolytic streptococci. The membrane-damaging activity is measured by hemolysis of red-blood cell. SLO is oxygen-sensitive and is easily inactivated in its presence but can be reactivated by thiol compounds , so it is also called thiol-activated cytolysin. SLO is produced not only by Group A hemolytic streptococci but also by Group C and Group G strains. The amino acid sequences are highly conserved among them and their homology is over 98%.
