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Pyripyropene A, ACAT2 inhibitor (ab144339)

Key features and details

  • Potent, selective ACAT2 inhibitor
  • CAS Number: 147444-03-9
  • Purity: > 95%
  • Soluble in DMSO
  • Form / State: Solid
  • Source: Aspergillus fumigatus

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Overview

  • Product name

    Pyripyropene A, ACAT2 inhibitor
  • Description

    Potent, selective ACAT2 inhibitor
  • Biological description

    Potent, selective ACAT2 inhibitor (IC50 = 70 nM). Shows antihypercholesterolemic and antiatherosclerotic effects in vivo. Orally active.
  • Purity

    > 95%
  • CAS Number

    147444-03-9
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    583.63
  • Molecular formula

    C31H37NO10
  • PubChem identifier

    54734280
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=O)OCC1(C(CCC2(C1C=C(C3(C2C(=C4C(=CC(OC4=O)C5=CN=CC=C5)O3)O)C)OC(=O)C)C)OC(=O)C)C
  • Source

    Aspergillus fumigatus

  • Research areas

    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cholesterol Metabolism
    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipoproteins/Apolipoproteins
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Cardiovascular
    • Atherosclerosis
    • Lipoprotein metabolism
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Cholesterol Metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipoprotein metabolism
    • Metabolism
    • Types of disease
    • Heart disease
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Transferase
    • General

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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