Pomalidomide, Antiangiogenic agent (ab143023)
Key features and details
- Inhibits LPS-induced TNF-α. Antiangiogenic agent.
- CAS Number: 19171-19-8
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pomalidomide, Antiangiogenic agent -
Description
Inhibits LPS-induced TNF-α. Antiangiogenic agent. -
Biological description
Inhibits LPS-induced TNF-α. Antiangiogenic agent. Thalidomide (ab120032) derivative. Shows antiproliferative and immunomodulatory effects in vivo. Orally active. -
Purity
> 99% -
CAS Number
19171-19-8 -
Chemical structure
Properties
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Chemical name
4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione -
Molecular weight
273.24 -
Molecular formula
C13H11N3O4 -
PubChem identifier
134780 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C2C(=C1N)C(N(C2=O)C3C(NC(CC3)=O)=O)=O -
Source
Synthetic
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Research areas
