PLX4720, B-Raf inhibitor (ab141362)
Key features and details
- Potent B-Raf inhibitor
- CAS Number: 918505-84-7
- Purity: > 95%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PLX4720, B-Raf inhibitor -
Description
Potent B-Raf inhibitor -
Biological description
Potent B-Raf inhibitor (IC50 values are 6.7, 13 and 160 nM for C-Raf-1Y340D/Y341D, B-RafV600E and B-Rafwild-type respectively). Shows antiproliferative effects. Shows antitumor effects in vivo. Orally active. -
Purity
> 95% -
CAS Number
918505-84-7 -
Chemical structure