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Cancer Cell cycle Kinases/phosphatases Cdks

PLX4720, B-Raf inhibitor (ab141362)

Key features and details

  • Potent B-Raf inhibitor
  • CAS Number: 918505-84-7
  • Purity: > 95%
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    PLX4720, B-Raf inhibitor
  • Description

    Potent B-Raf inhibitor
  • Biological description

    Potent B-Raf inhibitor (IC50 values are 6.7, 13 and 160 nM for C-Raf-1Y340D/Y341D, B-RafV600E and B-Rafwild-type respectively). Shows antiproliferative effects. Shows antitumor effects in vivo. Orally active.
  • Purity

    > 95%
  • CAS Number

    918505-84-7
  • Chemical structure

    Chemical Structure

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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