PJ34 hydrochloride, PARP-1 inhibitor (ab120981)
Key features and details
- Potent, selective PARP-1 inhibitor
- CAS Number: 344458-15-7
- Purity: > 98%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PJ34 hydrochloride, PARP-1 inhibitor -
Description
Potent, selective PARP-1 inhibitor -
Biological description
Potent, selective PARP-1 inhibitor (EC50 = 20 nM). Able to reduce both cell injury induced following deprivation of oxygen-glucose in vitro and infarct size following focal cerebral ischemia in vivo.
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Purity
> 98% -
CAS Number
344458-15-7 -
Chemical structure
Properties
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Chemical name
N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)acetamide hydrochloride -
Molecular weight
331.80 -
Molecular formula
C17H17N3O2.HCl -
PubChem identifier
16760621 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl -
Source
Synthetic
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Research areas
