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PIWIL3 overexpression 293T lysate (whole cell) (ab131153)

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Overview

  • Product name

    PIWIL3 overexpression 293T lysate (whole cell)
  • Tested applications

    Suitable for: WBmore details

Properties

  • Mycoplasma free

    Yes
  • Form

    Liquid
  • Storage instructions

    Shipped on dry ice. Upon delivery aliquot and store at -20ºC. Avoid freeze / thaw cycles.
  • Storage buffer

    Constituents: 0.01% Bromophenol blue, 2.34% Beta mercaptoethanol, 2% Sodium lauryl sulfate, 0.61% Tris, 10% Glycerol (glycerin, glycerine)
  • Concentration information loading...
  • Research areas

    • Stem Cells
    • Germline Stem Cells
    • Embryonic Germ Cells
    • Epigenetics and Nuclear Signaling
    • RNAi
    • Argonaute and Piwi
    • Developmental Biology
    • Reproduction
    • Germ cell markers
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Nuclear Pore Complex
  • Background

    Function: May play a role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Similarity: Belongs to the argonaute family. Piwi subfamily. Contains 1 PAZ domain. Contains 1 Piwi domain. Tissue specificity: Expressed in testis.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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