Pirarubicin, Topoisomerase II inhibitor (ab142734)
Key features and details
- Topoisomerase II inhibitor
- CAS Number: 72496-41-4
- Purity: > 90%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pirarubicin, Topoisomerase II inhibitor -
Description
Topoisomerase II inhibitor -
Biological description
Topoisomerase II inhibitor. Intercalates into DNA and inhibits DNA replication. Analogue of doxorubicin (ab120629). Expresses anti-tumor activity in vivo. -
Purity
> 90% -
CAS Number
72496-41-4 -
Chemical structure
Properties
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Chemical name
7-[4-Amino-6-methyl-5-(oxan-2-yloxy)oxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione -
Molecular weight
627.64 -
Molecular formula
C32H37NO12 -
PubChem identifier
4844 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6 -
Source
Synthetic
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Research areas