Pimozide, D2-receptor antagonist, antipsychotic agent (ab142135)
Key features and details
- D2-receptor antagonist, antipsychotic agent
- CAS Number: 2062-78-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Pimozide, D2-receptor antagonist, antipsychotic agent -
Description
D2-receptor antagonist, antipsychotic agent -
Biological description
D2-receptor antagonist. Antipsychotic agent. Binds with high affinity to the 5-HT7 receptor (Ki = 0.5 nM). Decrease STAT5 tyrosine phosphorylation. -
Purity
> 98% -
CAS Number
2062-78-4 -
Chemical structure
Properties
-
Chemical name
3-[1-[4,4-Bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one -
Molecular weight
461.55 -
Molecular formula
C28H29F2N3O -
PubChem identifier
16362 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F -
Source
Synthetic
-
Research areas