Pimobendan (Vetmedin), Ca2+ channel sensitizer (ab143019)
Key features and details
- Ca2+ channel sensitizer. Selective PDE3 inhibitor.
- CAS Number: 74150-27-9
- Purity: > 99%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pimobendan (Vetmedin), Ca2+ channel sensitizer -
Description
Ca2+ channel sensitizer. Selective PDE3 inhibitor. -
Biological description
Ca2+ channel sensitizer. Selective PDE3 inhibitor. Inhibits platelet aggregation. Shows antithrombotic, antihypertensive, potent inotropic and vasodilatory effects in vivo. Orally active.
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Purity
> 99% -
CAS Number
74150-27-9 -
Chemical structure
Properties
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Chemical name
4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl-3(2H)-pyridazinone -
Molecular weight
334.38 -
Molecular formula
C19H18N4O2 -
PubChem identifier
4823 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OC -
Source
Synthetic
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Research areas