Picrotoxin, GABAA antagonist (ab120315)
Key features and details
- GABAA antagonist
- CAS Number: 124-87-8
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 50 mM (with heating)
- Form / State: Solid
- Source: Anamirta cocculus
Overview
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Product name
Picrotoxin, GABAA antagonist -
Description
GABAA antagonist -
Biological description
Plant alkaloid. Non-competitive GABAA antagonist. Also inhibits homomeric glycine receptor. Convulsant in vivo.
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Purity
> 98% -
General notes
5g pack supplied as 5x1g
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CAS Number
124-87-8 -
Chemical structure
Properties
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Chemical name
1:1 mixture of picrotoxinin and picrotin -
Molecular weight
602.59 -
Molecular formula
C30H34O13 -
PubChem identifier
31304 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 50 mM (with heating) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=C)[C@@H]1C2[C@@H]3[C@@]4([C@](C1C(=O)O2)(CC5[C@]4(O5)C(=O)O3)O)C.C[C@@]12[C@H]3C4[C@H](C([C@@]1(C[C@@H]5[C@]2(O5)C(=O)O3)O)C(=O)O4)C(C)(C)O -
Source
Anamirta cocculus
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Research areas