PHCCC, allosteric potentiator at mGlu4 (ab120043)
Key features and details
- Selective allosteric potentiator at mGlu4. Also group I antagonist.
- CAS Number: 179068-02-1
- Purity: > 98%
Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PHCCC, allosteric potentiator at mGlu4 -
Description
Selective allosteric potentiator at mGlu4. Also group I antagonist. -
Biological description
Selective allosteric potentiator of mGlu4. Anti-Parkinson and anxiolytic effects in vivo. Also antagonist at Group I metabotropic receptors.
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Purity
> 98% -
CAS Number
179068-02-1 -
Chemical structure
Properties
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Chemical name
(E)-1,1a,7,7a-Tetrahydro-7-(hydroxyimino)-N-phenylcyclopropa[b]chromene-1a-carboxamide
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Molecular weight
294.31 -
Molecular formula
C17H14N2O3 -
PubChem identifier
5866327 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
ON=C1c4ccccc4OC2(CC12)C(=O)Nc3ccccc3 -
Source
Synthetic
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Research areas