PGP 4008, P-glycoprotein inhibitor (ab145191)
Key features and details
- Selective P-glycoprotein inhibitor
- CAS Number: 365565-02-2
- Purity: > 93%
- Soluble in ethanol to 5 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PGP 4008, P-glycoprotein inhibitor -
Description
Selective P-glycoprotein inhibitor -
Biological description
Selective P-glycoprotein inhibitor. Reverses Pgp mediated drug resistance in NCI/ADR cells. Shows synergistic effects with doxorubicin (ab120629) in vivo. -
Purity
> 93% -
CAS Number
365565-02-2 -
Chemical structure
Properties
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Chemical name
N-(1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide -
Molecular weight
393.49 -
Molecular formula
C26H23N3O -
PubChem identifier
9821937 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 5 mM and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN(C2=NC3=CC=CC=C3C(=C21)NC(=O)CC4=CC=CC=C4)CC5=CC=CC=C5 -
Source
Synthetic
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Research areas
