PD 153035 hydrochloride, EGFR tyrosine kinase inhibitor (ab142076)
Key features and details
- Highly potent, selective EGFR tyrosine kinase inhibitor
- CAS Number: 153436-54-5
- Purity: > 95%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PD 153035 hydrochloride, EGFR tyrosine kinase inhibitor -
Description
Highly potent, selective EGFR tyrosine kinase inhibitor -
Biological description
Highly potent, selective EGFR tyrosine kinase inhibitor (Ki value = 6 pM). Active in vitro and in vivo. -
Purity
> 95% -
CAS Number
153436-54-5 -
Chemical structure
Properties
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Chemical name
N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride -
Molecular weight
396.67 -
Molecular formula
C16H14BrN3O2.HCl -
PubChem identifier
11246488 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl -
Source
Synthetic
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Research areas
