PD 151746, Calpain inhibitor (ab145523)
Key features and details
- Cell permeable, selective, non-peptidic calpain inhibitor
- CAS Number: 179461-52-0
- Purity: > 96%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PD 151746, Calpain inhibitor -
Description
Cell permeable, selective, non-peptidic calpain inhibitor -
Biological description
Cell permeable, selective, non-peptidic calpain inhibitor (Ki values are 0.3 and 5 μM for calpain 1 and calpain 2, respectively). Stimulates phagocyte function via hFPR/hFPRL1 activation. Interacts with the Ca2+ calpain sites. Shows antiapoptotic effects.
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Purity
> 96% -
CAS Number
179461-52-0 -
Chemical structure
Properties
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Chemical name
3-(5-Fluoro-1H-indol-3-yl)-2-mercapto-2-propenoic acid -
Molecular weight
237.25 -
Molecular formula
C11H8FNO2S -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S -
Source
Synthetic
