Pancuronium dibromide, Competitive nicotinic acetylcholine receptor antagonist (ab120535)
Key features and details
- Competitive nicotinic acetylcholine receptor (nAChR) antagonist
- CAS Number: 15500-66-0
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Pancuronium dibromide, Competitive nicotinic acetylcholine receptor antagonist -
Description
Competitive nicotinic acetylcholine receptor (nAChR) antagonist -
Biological description
Competitive nicotinic acetylcholine receptor (nAChR) antagonist. Displaces acetylcholine (ab120469) from nAChRs (IC50 = 5.5 nM). Neuromuscular blocker and muscle relaxant.
-
CAS Number
15500-66-0 -
Chemical structure
Properties
-
Chemical name
1,1'-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide -
Molecular weight
732.68 -
Molecular formula
C35H60Br2N2O4 -
PubChem identifier
23581810 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
[Br-].[Br-].C[N+]1(CCCCC1)C6CC5(C)[C@@H](CCC2[C@@H]5CCC3(C)C(OC(C)=O)C(C[C@@H]23)[N+]4(C)CCCCC4)C[C@@H]6OC(C)=O -
Source
Synthetic
-
Research areas
