Pam3Cys-Ser-(Lys)4, TLR1/TLR2 agonist (ab142085)
Key features and details
- TLR1/TLR2 agonist
- CAS Number: 112208-00-1
- Purity: > 95%
- Soluble in 1:1 water/ethanol to 1 mg/ml
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pam3Cys-Ser-(Lys)4, TLR1/TLR2 agonist -
Description
TLR1/TLR2 agonist -
Alternative names
- pam3CSK4
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Biological description
TLR1/TLR2 agonist. Synthetic analog of the triacylated N-terminal part of bacterial lipoproteins. Potent adjuvant in vivo. Potent activator of Balb/c splenocytes.
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Purity
> 95% -
CAS Number
112208-00-1 -
Chemical structure
Properties
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Molecular weight
1510.24 -
Molecular formula
C81H156N10O13S -
Sequence
CSKKKK (Modifications: N-terminal palmitoyl; Cys-1 = Cys(2,3-Bis(palmitoyloxy)propyl)) -
PubChem identifier
130704 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1:1 water/ethanol to 1 mg/ml -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O -
Source
Synthetic
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Research areas