Paliperidone, D2 and 5-HT2A antagonist (ab142533)
Key features and details
- Atypical antipsychotic. Potent D2 and 5-HT2A antagonist.
- CAS Number: 144598-75-4
- Purity: > 98%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Paliperidone, D2 and 5-HT2A antagonist -
Description
Atypical antipsychotic. Potent D2 and 5-HT2A antagonist. -
Biological description
Atypical antipsychotic. Potent D2 and 5-HT2A antagonist (Ki = 0.4 nM for 5-HT2A). Metabolite of risperidone (Asc 393). Orally active and blood-brain barrier permeable. -
Purity
> 98% -
CAS Number
144598-75-4 -
Chemical structure
Properties
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Chemical name
3-[2-[4-(6-Fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one -
Molecular weight
426.48 -
Molecular formula
C23H27FN4O3 -
PubChem identifier
115237 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F -
Source
Synthetic
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Research areas
