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PACAP receptor/ADCYAP1R1 peptide (ab109076)

Description

Preparation and Storage

  • Alternative names

    • ADCYAP1 R1
    • ADCYAP1R 1
    • ADCYAP1R1
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
    • PAC 1
    • PAC1
    • PAC1R
    • PACAP receptor 1
    • PACAP type I receptor
    • PACAP-R-1
    • PACAP-R1
    • PACAP1 R
    • PACAPR
    • PACAPRI
    • PACR_HUMAN
    • Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop
    • Pituitary adenylate cyclase activating polypeptide receptor
    • Pituitary adenylate cyclase activating polypeptide type I receptor precursor
    • Pituitary adenylate cyclase-activating polypeptide 1, receptor for
    • Pituitary adenylate cyclase-activating polypeptide type I receptor
    • pvr1
    see all

  • Function

    This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.

  • Tissue specificity

    Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.

  • Sequence similarities

    Belongs to the G-protein coupled receptor 2 family.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

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