Osthole, anti-inflammatory and antitumor activities (ab143140)
Key features and details
- Bioactive coumarin. Anti-inflammatory and antitumor activity.
- CAS Number: 484-12-8
- Purity: > 99%
- Soluble in DMSO to 100 mM (with warming) and in ethanol to 100 mM (with warming)
- Form / State: Solid
- Source: Cnidium monnieri (L.) Cusson
Overview
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Product name
Osthole, anti-inflammatory and antitumor activities -
Description
Bioactive coumarin. Anti-inflammatory and antitumor activity. -
Biological description
Bioactive coumarin. Anti-inflammatory and antitumor activity. Phosphoinositide inhibitor and calcium channel blocker (IC50 = 4 μM). Suppresses NFκB activity to induce cell-cycle arrest and apoptosis in cancer cells. Anticoagulant, anti-inflammatory, neuroprotective and antitumor agent. Active in vivo and in vitro. -
Purity
> 99% -
CAS Number
484-12-8 -
Chemical structure
Properties
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Chemical name
7-Methoxy-8-(3-methylbut-2-enyl)chromen-2-one -
Molecular weight
244.29 -
Molecular formula
C15H16O3 -
PubChem identifier
10228 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM (with warming) and in ethanol to 100 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1(=CC=C2C(=C1CC=C(C)C)OC(C=C2)=O)OC -
Source
Cnidium monnieri (L.) Cusson
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Research areas
