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ORP150 peptide (ab156891)

Key features and details

  • Suitable for: Blocking

Description

Preparation and Storage

  • Alternative names

    • 150 kDa oxygen regulated protein
    • 150 kDa oxygen-regulated protein
    • 170 kDa glucose regulated protein
    • 170 kDa glucose-regulated protein
    • DKFZp686N08236
    • FLJ94899
    • FLJ97572
    • glucose regulated protein 170
    • Grp 170
    • GRP-170
    • Grp170
    • HSP 12A
    • HSP12A
    • Hyou1
    • HYOU1_HUMAN
    • Hypoxia up regulated 1
    • hypoxia up-regulated 1 precursor
    • Hypoxia up-regulated protein 1
    • Hypoxia upregulated 1
    • Orp 150
    • ORP-150
    • Orp150
    • oxygen regulated protein (150kD)
    see all

  • Function

    Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.

  • Tissue specificity

    Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.

  • Sequence similarities

    Belongs to the heat shock protein 70 family.

  • Cellular localization

    Endoplasmic reticulum lumen.
  • Information by UniProt

Images

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