Org 27569, CB1 receptor allosteric modulator (ab120342)
Key features and details
- Potent CB1 receptor allosteric modulator
- CAS Number: 868273-06-7
- Purity: > 99%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Org 27569, CB1 receptor allosteric modulator -
Description
Potent CB1 receptor allosteric modulator -
Biological description
Potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55,940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Behaves as an insurmountable antagonist of receptor function in in vitro assays.
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Purity
> 99% -
CAS Number
868273-06-7 -
Chemical structure
Properties
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Chemical name
5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl]-1H-indole-2-carboxamide -
Molecular weight
409.96 -
Molecular formula
C24H28ClN3O -
PubChem identifier
44828492 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Clc1cc2c(CC)c(nc2cc1)C(=O)NCCc3ccc(cc3)N4CCCCC4 -
Source
Synthetic
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Research areas
