Onalespib (AT13387) (ab273524)
Key features and details
- Potent Hsp90 inhibitor
- CAS Number: 912999-49-6
- Purity: >= 98%
Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Onalespib (AT13387) -
Description
Potent Hsp90 inhibitor -
Biological description
Potent Hsp90 inhibitor (IC50 = 18 nM). Inhibits PDGF-BB-stimulated cell migration and p44/p42 MAP kinase phosphorylation.
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Purity
>= 98% -
General notes
Protect from air.
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CAS Number
912999-49-6 -
Chemical structure
Properties
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Chemical name
[1,3-Dihydro-5-[(4-methyl-1-piperazinyl)methyl]-2H-isoindol-2-yl][2,4- dihydroxy-5-(1-methylethyl)phenyl]methanone
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Molecular weight
409.50 -
Molecular formula
C24H31N3O3 -
PubChem identifier
11955716 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store In the Dark. -
Solubility overview
Soluble in DMSO to 10 mM
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Handling
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)C1=CC(=C(C=C1O)O)C(=O)N2CC3=C(C2)C=C(C=C3)CN4CCN(CC4)C -
Source
Synthetic
Images
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Chemical Structure - Onalespib (AT13387) (ab273524)
Chemical structure of Onalespib (AT13387), 912999-49-6
