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Onalespib (AT13387) (ab273524)

Key features and details

  • Potent Hsp90 inhibitor
  • CAS Number: 912999-49-6
  • Purity: >= 98%

  • Soluble in DMSO to 10 mM

  • Form / State: Solid
  • Source: Synthetic

Overview

  • Product name

    Onalespib (AT13387)

  • Description

    Potent Hsp90 inhibitor

  • Biological description

    Potent Hsp90 inhibitor (IC50 = 18 nM). Inhibits PDGF-BB-stimulated cell migration and p44/p42 MAP kinase phosphorylation.

  • Purity

    >= 98%

  • General notes

    Protect from air.

  • CAS Number

    912999-49-6

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [1,3-Dihydro-5-[(4-methyl-1-piperazinyl)methyl]-2H-isoindol-2-yl][2,4- dihydroxy-5-(1-methylethyl)phenyl]methanone

  • Molecular weight

    409.50

  • Molecular formula

    C24H31N3O3

  • PubChem identifier

    11955716

  • Storage instructions

    Shipped at 4°C. Store at -20°C. Store In the Dark.

  • Solubility overview

    Soluble in DMSO to 10 mM

  • Handling

    Refer to SDS for further information

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)C1=CC(=C(C=C1O)O)C(=O)N2CC3=C(C2)C=C(C=C3)CN4CCN(CC4)C

  • Source

    Synthetic

Images

  • Chemical Structure - Onalespib (AT13387) (ab273524)
    Chemical Structure - Onalespib (AT13387) (ab273524)

    Chemical structure of Onalespib (AT13387), 912999-49-6

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