Olomoucine, ATP-competitive CDK inhibitor (ab120938)
Key features and details
- ATP-competitive CDK inhibitor
- CAS Number: 101622-51-9
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Olomoucine, ATP-competitive CDK inhibitor -
Description
ATP-competitive CDK inhibitor -
Biological description
ATP-competitive CDK inhibitor (IC50 values are 7 (CDC2/cyclin B), 7 (CDK2/cyclin A), 7 (CDK2/cyclin E), 3 (CDK/p35 kinase) and 25 μM (ERK1/p44 MAPK)). Inhibits cell cycle progression in vitro and in vivo. -
Purity
> 98% -
CAS Number
101622-51-9 -
Chemical structure
Properties
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Chemical name
6-Benzylamino-2-(2-hydroxyethylamino)-9-methylpurine -
Molecular weight
298.35 -
Molecular formula
C15H18N6O -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
OCCNc1nc(NCc2ccccc2)c2ncn(C)c2n1 -
Source
Synthetic
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Research areas