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O-1602, GPR55 agonist (ab120407)

Key features and details

  • Potent, selective GPR55 agonist
  • CAS Number: 317321-41-8
  • Purity: > 98%
  • Supplied in methyl acetate (10 mg/ml)
  • Form / State: Liquid
  • Source: Synthetic

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Overview

  • Product name

    O-1602, GPR55 agonist
  • Description

    Potent, selective GPR55 agonist
  • Biological description

    Analog of cannabidiol that is a potent agonist at the GPR55 cannabinoid receptor (EC50 values are 13, >30000 and >30000 nM for GPR55, CB1 and CB2 receptors, respectively). Inhibits mouse osteoclast formation in vitro, stimulates osteoclast polarization and resorption, causes activation of Rho and ERK1/2, and inhibits human neutrophil migration.

  • Purity

    > 98%
  • General notes

    Sold under license from Virginia Commonwealth University.
  • CAS Number

    317321-41-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-Methyl-4-((1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-enyl)benzene-1,3-diol
  • Molecular weight

    258.36
  • Molecular formula

    C17H22O2
  • PubChem identifier

    45073499
  • Storage instructions

    Store at -20°C (desiccating conditions).
  • Solubility overview

    Supplied in methyl acetate (10 mg/ml)
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=C)[C@@H]2CCC(C)=C[C@H]2c1c(C)cc(O)cc1O
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Cannabinoid Receptor
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Cannabinoid
    • GPR55
    • Agonists
    • Biochemicals
    • Research Area
    • Addiction
    • Cannabinoid
    • GPR55
    • Agonists
    • Biochemicals
    • Research Area
    • Obesity
    • Cannabinoid
    • GPR55
    • Agonists
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Cannabinoid
    • GPR55
    • Agonists

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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