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Signal Transduction Signaling Pathway Calcium Signaling Calpain

NYC-488, Calpain Inhibitor, calpain inhibitor (ab143563)

Price and availability

154 118 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • Novel, selective calpain inhibitor
  • CAS Number: 1448429-06-8
  • Purity: > 94%
  • Soluble in DMSO

  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    NYC-488, Calpain Inhibitor, calpain inhibitor
  • Description

    Novel, selective calpain inhibitor
  • Alternative names

    • NYC488
  • Biological description

    Novel, selective calpain inhibitor. Possible therapeutic agent against Alzheimer’s disease.

  • Purity

    > 94%
  • CAS Number

    1448429-06-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S,3S)-3-((S)-1-((1-(4-Fluorophenyl)-1H-1,2,3-triazol-4-yl)-methylamino)-1-oxo-3-(thiazol-4-yl)propan-2-ylcarbamoyl)-oxirane-2-carboxylic acid

  • Molecular weight

    460.44
  • Molecular formula

    C19H17FN6O5S
  • PubChem identifier

    71660816
  • Storage instructions

    Store at -20°C.
  • Solubility overview

    Soluble in DMSO

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Fc1ccc(cc1)n2cc(nn2)CNC(=O)[C@@H](NC(=O)[C@H]3O[C@@H]3C(=O)O)Cc4cscn4
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • Calcium Signaling
    • Calpain
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteolytic enzymes
    • Cysteine protease
    • Calpains

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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