Norquetiapine dihydrochloride, NET inhibitor (ab145621)
Key features and details
- Selective NET inhibitor. Partial 5-HT1A receptor agonist.
- CAS Number: 111974-74-4
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Norquetiapine dihydrochloride, NET inhibitor -
Description
Selective NET inhibitor. Partial 5-HT1A receptor agonist. -
Biological description
Selective NET inhibitor. Partial 5-HT1A receptor agonist. Presynaptic α2, 5-HT2C, and 5-HT7 receptor antagonist. Quetiapine (ab120737) active metabolite. Shows antidepressant effects in vivo. -
Purity
> 98% -
CAS Number
111974-74-4 -
Chemical structure
Properties
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Chemical name
6-Piperazin-1-ylbenzo[b][1,4]benzothiazepine dihydrochloride -
Molecular weight
368.32 -
Molecular formula
C17H17N3S.2HCl -
PubChem identifier
19842188 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN(CCN1)C2=NC3=CC=CC=C3SC4=CC=CC=C42.Cl.Cl -
Source
Synthetic
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Research areas
