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Neuroscience Neurotransmission Receptors / Channels Potassium Channels

Nobiletin, Matrix metalloprotease (MMP) inhibitor (ab142927)

Key features and details

  • Polymethoxylated flavone. Potent MMP inhibitor.
  • CAS Number: 478-01-3
  • Purity: > 97%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Nobiletin, Matrix metalloprotease (MMP) inhibitor
  • Description

    Polymethoxylated flavone. Potent MMP inhibitor.
  • Biological description

    Polymethoxylated flavone. Potent MMP inhibitor. Inhibits proMMP-1, 3, and 9 production. Shows anti-inflammatory and antitumor effects in vivo. Orally active.
  • Purity

    > 97%
  • CAS Number

    478-01-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one
  • Molecular weight

    402.39
  • Molecular formula

    C21H22O8
  • PubChem identifier

    72344
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)OC
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Potassium Channels
    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Signal Transduction
    • Metabolism
    • Plasma Membrane
    • Channels
    • Cardiovascular
    • Blood
    • Blood Pressure regulation
    • Cardiovascular
    • Vasculature
    • Vasoconstriction
    • Other
    • Cardiovascular
    • Vasculature
    • Vasodilation
    • Other
    • Cancer
    • Cancer Metabolism
    • Response to hypoxia
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Hypoxia
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Protease
    • Matrix metalloprotease
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Extracellular matrix & cell adhesion
    • Matrix metalloprotease

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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