N,N-Dimethyl-D-erythro-sphingosine (PKC inhibitor), Sphingosine kinase and PKC inhibitor (ab141237)
Key features and details
- Sphingosine kinase and PKC inhibitor
- CAS Number: 119567-63-4
- Purity: > 98%
- Supplied in isopropanol (5 mg/ml)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
N,N-Dimethyl-D-erythro-sphingosine (PKC inhibitor), Sphingosine kinase and PKC inhibitor -
Description
Sphingosine kinase and PKC inhibitor -
Biological description
Inhibitor of sphingosine kinase (IC50=5 µM) and PKC (IC50=12 µM). Blocks conversion of sphingosine to sphingosine-1-phosphate. Induces apoptosis and EGFR autophosphorylation. Produced via ceramide catabolism. Active in vitro. -
Purity
> 98% -
CAS Number
119567-63-4 -
Chemical structure
Properties
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Chemical name
(E,2S,3R)-2-(Dimethylamino)octadec-4-ene-1,3-diol -
Molecular weight
327.55 -
Molecular formula
C20H41NO2 -
PubChem identifier
5282309 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Supplied in isopropanol (5 mg/ml) -
Handling
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SMILES
CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)N(C)C)O -
Source
Synthetic
