NKH 477 (Colforsin daropate), an adenylyl cyclase activator (ab120190)
Key features and details
- Water-soluble analogue of forskolin (ab120058), an adenylyl cyclase activator
- CAS Number: 138605-00-2
- Soluble in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
NKH 477 (Colforsin daropate), an adenylyl cyclase activator -
Description
Water-soluble analogue of forskolin (ab120058), an adenylyl cyclase activator -
Alternative names
- Colforsin daropate hydrochloride
-
Biological description
Water-soluble adenylyl cyclase activator
-
CAS Number
138605-00-2 -
Chemical structure
Properties
-
Chemical name
N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester β-alanine hydrochloride -
Molecular weight
546.10 -
Molecular formula
C27H43NO8.HCl -
PubChem identifier
444028 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
Cl.CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]3(C)O[C@@](C)(C=C)CC(=O)[C@]3(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12 -
Source
Synthetic
-
Research areas
- Biochemicals
- Pharmacology
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Heart disease
- Signaling
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Pain & inflammation
- Signaling
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Obesity
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Respiratory disease
- Signaling
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators