Necrostatin-5, Necroptosis inhibitor (ab142131)
Key features and details
- Necroptosis inhibitor
- CAS Number: 337349-54-9
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Necrostatin-5, Necroptosis inhibitor -
Description
Necroptosis inhibitor -
Biological description
Inhibitor of necroptosis (non-apoptotic cell death pathway) by indirect inhibition of RIP1 kinase. -
Purity
> 98% -
CAS Number
337349-54-9 -
Chemical structure
Properties
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Chemical name
2-[[3-(4-Methoxyphenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetonitrile -
Molecular weight
383.49 -
Molecular formula
C19H17N3O2S2 -
PubChem identifier
1913406 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=CC=C(C=C1)N2C(=O)C3=C(N=C2SCC#N)SC4=C3CCCC4 -
Source
Synthetic
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Research areas
