Native Rat Transferrin protein (ab198663)
Key features and details
- Expression system: Native
- Purity: >= 98% SDS-PAGE
- Suitable for: SDS-PAGE
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Product name
Native Rat Transferrin protein
See all Transferrin proteins and peptides -
Purity
>= 98 % SDS-PAGE. -
Expression system
Native -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Native -
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Species
Rat -
Predicted molecular weight
80 kDa -
Additional sequence information
Prepared from rat plasma.
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Preparation and Storage
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Alternative names
- Apotransferrin
- Beta 1 metal binding globulin
- Beta-1 metal-binding globulin
see all -
Function
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. -
Tissue specificity
Expressed by the liver and secreted in plasma. -
Involvement in disease
Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. -
Sequence similarities
Belongs to the transferrin family.
Contains 2 transferrin-like domains. -
Cellular localization
Secreted. - Information by UniProt
Images
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SDS-PAGE - Native Rat Transferrin protein (ab198663)
SDS PAGE analysis of ab198663:
Lane 1: 5 μg, under reduced and heated conditions;
Lane 2: 10 μg, under reduced and heated conditions;
Lane 3: 20 μg, under reduced and heated conditions.
Lane 4: 5 μg, under non reduced and not heated conditions;
Lane 5: 10 μg, under non reduced and not heated conditions;
Lane 6: 20 μg, under non reduced and not heated conditions.
