• Product name

  Native Human Urokinase protein (HRP)
  See all Urokinase proteins and peptides

• Purity

  > 95 % SDS-PAGE.
  
  

• Expression system

  Native

• Accession

  P00749

• Protein length

  Full length protein

• Animal free

  No

• Nature

  Native

• • Species

    Human

• Conjugation

  HRP

• Alternative names

  • ATF
  • ATF uPA
  • BDPLT5

  • Plasminogen activator
  • Plasminogen activator urinary
  • Plasminogen activator urokinase
  • PLAU
  • QPD
  • u PA
  • U plasminogen activator
  • u-PA
  • U-plasminogen activator
  • uPA
  • URK
  • UROK_HUMAN
  • Urokinase plasminogen activator
  • Urokinase type plasminogen activator
  • Urokinase type plasminogen activator precursor
  • Urokinase-type plasminogen activator chain B

  see all

• Function

  Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.

• Tissue specificity

  Expressed in the prostate gland and prostate cancers.

• Sequence similarities

  Belongs to the peptidase S1 family.
  Contains 1 EGF-like domain.
  Contains 1 kringle domain.
  Contains 1 peptidase S1 domain.

• Post-translational
  modifications

  Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.

• Cellular localization

  Secreted.

• Target information above from: UniProt accession P00749 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt